Neurodegeneration

Treating nature with NURTURE: Interim results of nusinersen for SMA

3473 2300 Mea Holm, PhD

Promising results for a disease-modifying treatment for spinal muscular atrophy (SMA) were presented at the 5th Annual Congress of the European Academy of Neurology (EAN) in Oslo, Norway, last week.…

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Serum NfL levels shine a light on neuroaxonal damage and disease

4089 2300 Michael Furrer, PhD

The 5th Annual Congress of the European Academy of Neurology (EAN) in Oslo, Norway, featured an in-depth exploration of the role of neurofilament light chain (NfL) protein levels as a…

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Cellular power failures linked to Parkinsonism

3150 2100 Mea Holm, PhD

Mounting evidence is linking neurodegenerative disorders, such as Parkinsonism and dementia, with mitochondrial dysfunction.1 At the 5th Annual Congress of the European Academy of Neurology (EAN) in Oslo, Norway, the…

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lab

Establishing sNfL as an MS Biomarker

3300 2200 Carlotta Foletti, PhD

At the ECTRIMS annual congress in October 2018, there was a lot of talk on serum neurofilament light (sNfL) becoming the first blood biomarker predicting neuronal damage caused by neurological…

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news

News from the ocrelizumab front

3300 2200 Carlotta Foletti, PhD

In our ongoing coverage of the AAN Annual Meeting in Philadelphia, we are focusing on select posters reporting on studies of ocrelizumab, an intravenous humanised monoclonal antibody that selectively targets…

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Will new understanding equal new treatments for toxic ALS mutation?

3139 2200 Peter Stevenson, PhD

Researchers may have solved the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis (ALS), marking out new territory in which to explore possible treatments. ALS, also known…

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Young neurons in mature brains

3150 2100 Peter Stevenson, PhD

A new study uncovered the existence of immature neurons in adult brains well into old age, adding more weight to the longstanding debate of whether neurogenesis really stops after adolescence.…

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Could the gut-brain axis have a role in stroke recovery?

3300 2200 Peter Stevenson, PhD

Acute disruption of bacterial populations in the gut after stroke could have a detrimental effect on recovery, according to new research. The role that our microbiome – the microbial environment…

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Genetic link uncovered that could help protect against PTSD

3150 2100 Peter Stevenson, PhD

A new study has identified a link between fear memory and TIA1, a prion-related RNA-binding protein whose capacity to form various types of intracellular aggregates has been implicated in neurodegenerative…

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FDA issues warnings on illegal Alzheimer’s drugs

2880 1920 Peter Stevenson, PhD

On 11 February 2019, the United States Food and Drug Administration (FDA) issued warnings to 17 companies that illegally sold more than 50 products claiming to prevent, treat or cure…

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