Multiple sclerosis

Ageing in multiple sclerosis – what do we know?

2846 1601 Anna Stelling, PhD

“Ageing comes with many issues in multiple sclerosis (MS): progression, comorbidities, cognition problems and response to treatment”, Pierre Duquette (Department of Neuroscience, University of Montreal, Canada), the chair of the…

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How to promote remyelination in MS

2846 1601 Anne Carter, MA (Cantab)

Strategies to promote remyelination was a hot topic at this year’s virtual ACTRIMS/ECTRIMS joint meeting, with three expert presenters each addressing a different aspect of the subject, including the role…

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Does the microbiome have a role in MS?

2846 1600 Anne Carter, MA (Cantab)

Can the bacteria living in your gut influence multiple sclerosis (MS) susceptibility and risk of relapse? That was the question Emmanuelle Waubant (University of California, San Francisco, USA) posed during…

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Is disease-modifying treatment in primary progressive multiple sclerosis effective after all?

1703 2560 Anna Stelling, PhD

Until now, several randomised controlled trials and real-world studies could not show the clinical benefit of disease‑modifying treatments (DMTs) in primary progressive multiple sclerosis (PPMS).1-4 However, some recently published results…

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Neurofilament light chain levels as a biomarker in multiple sclerosis

1703 2560 Anna Stelling, PhD

It has been previously shown that the neuronal cytoskeletal protein neurofilament light chain (NfL) is released into the blood and cerebrospinal fluid (CSF) upon neuroaxonal injury.1 Hence it was not…

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Do hormonal changes influence MS in women?

2400 1600 Anne Carter, MA (Cantab)

There is a paradox in multiple sclerosis (MS): females appear to be more susceptible to the disease than males, but also have a better long-term prognosis. Could this be due…

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Sun, ray of light, forest, trees

Siponimod shows promising long-term efficacy in SPMS patients

1920 1280 Anna Stelling, PhD

While researchers are looking at the potential of stem cells in the treatment of multiple sclerosis (MS), novel, promising immune-modulating therapies are being developed. At this year’s virtual EAN Congress,…

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Paediatric multiple sclerosis: Adding to our knowledge

1920 1080 Anne Carter, MA (Cantab)

Data suggest that between 2 and 5% of patients with multiple sclerosis (MS) are under 18 years old,1 yet there is only one approved treatment option in this population.2,3 During…

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Why B-cell therapies, or why not?

3848 2300 Peter Stevenson, PhD

The rational for B-cell therapy in multiple sclerosis (MS) was presented during ECTRIMS 2019, with David Baker (Blizard Institute, Queen Mary University of London, UK) posing the question of why…

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Are stem cells in MS ready for prime time?

2300 1535 Peter Stevenson, PhD

Hot topics continued at ECTRIMS 2019 in Stockholm with Joachim Burman (Department of Neurology, Uppsala University Hospital, Sweden), who stepped up to the podium to discuss autologous haematopoietic stem cell transplantation (aHSCT)…

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