ECTRIMS 2021

Getting the complete clinical picture: A closer look at smouldering MS

6641 3734 Howard Donohue, PhD

Multiple sclerosis (MS) is an inflammatory disease that is often dominated by relapsing-remitting symptoms.1 However, inflammation is not only present in acute and relapsing MS, but also in the secondary…

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Expanded interval dosing of natalizumab: Outcomes from the NOVA study

6641 3734 Howard Donohue, PhD

Natalizumab 300 mg every 4 weeks (Q4W) is approved for the treatment of relapsing-remitting multiple sclerosis (MS). In patients previously exposed to the JC virus, natalizumab is associated with a…

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Aquaporin-4-positive neuromyelitis optica spectrum disorder: A favourable long-term benefit-risk profile of eculizumab treatment

6641 3734 Howard Donohue, PhD

Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon inflammatory disease that typically affects the optic nerves and spinal cord.1,2 At least two-thirds of cases are associated with aquaporin-4 (AQP4) antibodies…

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Integrative medicine for multiple sclerosis: Outcomes from the Inspire MS program

5692 3201 Howard Donohue, PhD

A growing body of evidence suggests that integrative medicine (IM) modalities can enhance the comprehensive care of patients with multiple sclerosis (MS). Thirty to eighty percent of patients with MS…

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To stay or to switch? Assessing long-term treatment outcomes and impact of treatment on patients’ quality of life

6641 3734 Howard Donohue, PhD

The main concerns of patients, regarding their treatment, include disease control and safety, but they also want to make sure that their day-to-day life remains as close to normal as…

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