Journal watch: Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases

850 567 Shawn Haigh

The Background 2-Deoxy-2-[18F]fluoro-d-glucose positron emission tomography (FDG-PET) is a commonly used method to detect regional reductions in brain glucose uptake typically observed in patients with Alzheimer’s disease (AD) and other…

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How does aerobic exercise impact motor symptom progression in individuals with Parkinson’s disease?

1134 755 Maggie Ford, MD

Previous studies have shown that physical exercise can improve motor symptoms in Parkinson’s disease (PD).1,2 In a recent single-centre, prospective, Phase 2, double-blind, randomised, placebo-controlled trial called Park-in-Shape, Van der…

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Journal watch: The neuropsychiatry of Parkinson’s disease: advances and challenges

850 567 Maggie Ford, MD

The Background Although Parkinson’s disease (PD) is well known for its motor symptoms its associated neuropsychiatric symptoms should not be overlooked.1 Neuropsychiatric symptoms are common in all stages of PD,…

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Swiss study reveals shorter duration of intensive care unit and hospital stays with direct and early induction of artificial coma in status epilepticus

2560 1709 Maggie Ford, MD

Status epilepticus (SE) is a lethal, life-threatening neurologic emergency associated with high levels of morbidity and mortality.1-3 International treatment guidelines recommend the use of benzodiazepines as first-line treatment followed by…

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What is the link between the gut microbiome and Alzheimer’s disease?

2560 1920 Maggie Ford, MD

Adding to Brainwork’s existing dossier of articles covering the relationship between neurological conditions and the gastrointestinal tract,1-4 the present article will examine a connection between the gut microbiome and Alzheimer’s…

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Is it the chicken or the egg: a causality dilemma, which comes first dementia or epilepsy?

2560 1702 Maggie Ford, MD

Epilepsy with dementia or dementia with epilepsy Two recent studies have had contradictory results regarding the relationship between dementia and epilepsy.1,2 Johnson et al. 2020 found that 41.6% of participants…

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Journal watch: Long-term risk of Parkinson disease following influenza and other infections

2560 1700 Maggie Ford, MD

The Background The connections between prior influenza and other infections to the risk of developing Parkinson disease (PD) have been contentious.1   The Objective This case-control study addresses the association…

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Neuropalliative care: a new field and a new way to improve patient quality of life

2560 1920 Maggie Ford, MD

The missing link between neurology and palliative care Neuropalliative care is a young and developing subspecialty of both palliative care and neurology, in which the principles of palliative care are…

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Journal watch: Effect of cannabidiol on interictal epileptiform activity and sleep architecture in children with intractable epilepsy: A prospective open-label study

1500 1000 Shawn Haigh

The Background Cannabidiol was used increasingly over the last 5 years in the therapy of epilepsy and has shown to be effective in reducing seizures in patients with Dravet syndrome,…

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Speaking to Prof. Georgia Ramantani — “Curing children provides hope for the future”

1000 667 Anna Stelling, PhD

Prof. Georgia Ramantani, MD, PhD, is a paediatrician, paediatric neurologist, epileptologist and neurophysiologist currently heading the division of EEG & Epilepsy at the Department of Neuropaediatrics, University Children’s Hospital Zurich,…

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